Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond

DNA damage response (DDR) and apoptosis are reported to be involved in the pathogenesis of many neurodegenerative diseases including polyglutamine (polyQ) disorders, such as Spinocerebellar ataxia type 3 (SCA3) and Huntington's disease (HD). Consistently, an increasing body of studies provide c...

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Detalles Bibliográficos
Autores principales: Tu, Yingfeng, Li, Xiaoling, Zhu, Xuefei, Liu, Xiaokang, Guo, Caixia, Jia, Da, Tang, Tie-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793700/
https://www.ncbi.nlm.nih.gov/pubmed/33425926
http://dx.doi.org/10.3389/fcell.2020.619911

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