Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile m...

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Detalles Bibliográficos
Autores principales: Mincham, Kyle T., Jones, Anya C., Bodinier, Marie, Scott, Naomi M., Lauzon-Joset, Jean-Francois, Stumbles, Philip A., Bosco, Anthony, Holt, Patrick G., Strickland, Deborah H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793790/
https://www.ncbi.nlm.nih.gov/pubmed/33424847
http://dx.doi.org/10.3389/fimmu.2020.601494

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