Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy

Early TCR signaling is dependent on rapid phosphorylation and dephosphorylation of multiple signaling and adaptor proteins, leading to T cell activation. This process is tightly regulated by an intricate web of interactions between kinases and phosphatases. A number of tyrosine phosphatases have bee...

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Detalles Bibliográficos
Autores principales: Castro-Sanchez, Patricia, Teagle, Alexandra R., Prade, Sonja, Zamoyska, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793860/
https://www.ncbi.nlm.nih.gov/pubmed/33425916
http://dx.doi.org/10.3389/fcell.2020.608747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793860/
https://www.ncbi.nlm.nih.gov/pubmed/33425916
http://dx.doi.org/10.3389/fcell.2020.608747

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