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hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways

Background: Human bone marrow-derived mesenchymal stromal cells (hBMSCs) provide a promising therapeutic approach in the cell-based therapy of osteoarthritis (OA). However, several disadvantages evolved recently, including immune responses of the host and regulatory hurdles, making it necessary to s...

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Detalles Bibliográficos
Autores principales:	Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Götz, Julia, Herrmann, Marietta, Federlin, Marianne, Grässel, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793861/ https://www.ncbi.nlm.nih.gov/pubmed/33425869 http://dx.doi.org/10.3389/fbioe.2020.603598

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