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Extracellular Citrate Fuels Cancer Cell Metabolism and Growth
Cancer cells need excess energy and essential nutrients/metabolites not only to divide and proliferate but also to migrate and invade distant organs for metastasis. Fatty acid and cholesterol synthesis, considered a hallmark of cancer for anabolism and membrane biogenesis, requires citrate. We revie...
Autores principales: | Haferkamp, Sebastian, Drexler, Konstantin, Federlin, Marianne, Schlitt, Hans J., Berneburg, Mark, Adamski, Jerzy, Gaumann, Andreas, Geissler, Edward K., Ganapathy, Vadivel, Parkinson, E. Kenneth, Mycielska, Maria E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793864/ https://www.ncbi.nlm.nih.gov/pubmed/33425906 http://dx.doi.org/10.3389/fcell.2020.602476 |
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