Nanocarrier vaccines for SARS-CoV-2

The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death associated with substantive social, economic and societal impacts. Treatments rely on re-purposed antivirals and immune modulatory agents focusing on attenuating the acute respiratory distress syndrome. No curative t...

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Autores principales: Machhi, Jatin, Shahjin, Farah, Das, Srijanee, Patel, Milankumar, Abdelmoaty, Mai Mohamed, Cohen, Jacob D., Singh, Preet Amol, Baldi, Ashish, Bajwa, Neha, Kumar, Raj, Vora, Lalit K., Patel, Tapan A., Oleynikov, Maxim D., Soni, Dhruvkumar, Yeapuri, Pravin, Mukadam, Insiya, Chakraborty, Rajashree, Saksena, Caroline G., Herskovitz, Jonathan, Hasan, Mahmudul, Oupicky, David, Das, Suvarthi, Donnelly, Ryan F., Hettie, Kenneth S., Chang, Linda, Gendelman, Howard E., Kevadiya, Bhavesh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794055/
https://www.ncbi.nlm.nih.gov/pubmed/33428995
http://dx.doi.org/10.1016/j.addr.2021.01.002
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author Machhi, Jatin
Shahjin, Farah
Das, Srijanee
Patel, Milankumar
Abdelmoaty, Mai Mohamed
Cohen, Jacob D.
Singh, Preet Amol
Baldi, Ashish
Bajwa, Neha
Kumar, Raj
Vora, Lalit K.
Patel, Tapan A.
Oleynikov, Maxim D.
Soni, Dhruvkumar
Yeapuri, Pravin
Mukadam, Insiya
Chakraborty, Rajashree
Saksena, Caroline G.
Herskovitz, Jonathan
Hasan, Mahmudul
Oupicky, David
Das, Suvarthi
Donnelly, Ryan F.
Hettie, Kenneth S.
Chang, Linda
Gendelman, Howard E.
Kevadiya, Bhavesh D.
author_facet Machhi, Jatin
Shahjin, Farah
Das, Srijanee
Patel, Milankumar
Abdelmoaty, Mai Mohamed
Cohen, Jacob D.
Singh, Preet Amol
Baldi, Ashish
Bajwa, Neha
Kumar, Raj
Vora, Lalit K.
Patel, Tapan A.
Oleynikov, Maxim D.
Soni, Dhruvkumar
Yeapuri, Pravin
Mukadam, Insiya
Chakraborty, Rajashree
Saksena, Caroline G.
Herskovitz, Jonathan
Hasan, Mahmudul
Oupicky, David
Das, Suvarthi
Donnelly, Ryan F.
Hettie, Kenneth S.
Chang, Linda
Gendelman, Howard E.
Kevadiya, Bhavesh D.
author_sort Machhi, Jatin
collection PubMed
description The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death associated with substantive social, economic and societal impacts. Treatments rely on re-purposed antivirals and immune modulatory agents focusing on attenuating the acute respiratory distress syndrome. No curative therapies exist. Vaccines remain the best hope for disease control and the principal global effort to end the pandemic. Herein, we summarize those developments with a focus on the role played by nanocarrier delivery.
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spelling pubmed-77940552021-01-11 Nanocarrier vaccines for SARS-CoV-2 Machhi, Jatin Shahjin, Farah Das, Srijanee Patel, Milankumar Abdelmoaty, Mai Mohamed Cohen, Jacob D. Singh, Preet Amol Baldi, Ashish Bajwa, Neha Kumar, Raj Vora, Lalit K. Patel, Tapan A. Oleynikov, Maxim D. Soni, Dhruvkumar Yeapuri, Pravin Mukadam, Insiya Chakraborty, Rajashree Saksena, Caroline G. Herskovitz, Jonathan Hasan, Mahmudul Oupicky, David Das, Suvarthi Donnelly, Ryan F. Hettie, Kenneth S. Chang, Linda Gendelman, Howard E. Kevadiya, Bhavesh D. Adv Drug Deliv Rev Article The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death associated with substantive social, economic and societal impacts. Treatments rely on re-purposed antivirals and immune modulatory agents focusing on attenuating the acute respiratory distress syndrome. No curative therapies exist. Vaccines remain the best hope for disease control and the principal global effort to end the pandemic. Herein, we summarize those developments with a focus on the role played by nanocarrier delivery. Published by Elsevier B.V. 2021-04 2021-01-09 /pmc/articles/PMC7794055/ /pubmed/33428995 http://dx.doi.org/10.1016/j.addr.2021.01.002 Text en Crown Copyright © 2021 Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Machhi, Jatin
Shahjin, Farah
Das, Srijanee
Patel, Milankumar
Abdelmoaty, Mai Mohamed
Cohen, Jacob D.
Singh, Preet Amol
Baldi, Ashish
Bajwa, Neha
Kumar, Raj
Vora, Lalit K.
Patel, Tapan A.
Oleynikov, Maxim D.
Soni, Dhruvkumar
Yeapuri, Pravin
Mukadam, Insiya
Chakraborty, Rajashree
Saksena, Caroline G.
Herskovitz, Jonathan
Hasan, Mahmudul
Oupicky, David
Das, Suvarthi
Donnelly, Ryan F.
Hettie, Kenneth S.
Chang, Linda
Gendelman, Howard E.
Kevadiya, Bhavesh D.
Nanocarrier vaccines for SARS-CoV-2
title Nanocarrier vaccines for SARS-CoV-2
title_full Nanocarrier vaccines for SARS-CoV-2
title_fullStr Nanocarrier vaccines for SARS-CoV-2
title_full_unstemmed Nanocarrier vaccines for SARS-CoV-2
title_short Nanocarrier vaccines for SARS-CoV-2
title_sort nanocarrier vaccines for sars-cov-2
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794055/
https://www.ncbi.nlm.nih.gov/pubmed/33428995
http://dx.doi.org/10.1016/j.addr.2021.01.002
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