The Intraprostatic Immune Environment after Stereotactic Body Radiotherapy is Dominated by Myeloid Cells

BACKGROUND: Hundreds of ongoing clinical trials combine radiation therapy, mostly delivered as stereotactic body radiotherapy (SBRT), with immune checkpoint blockade. However, our understanding of the effect of radiotherapy on the intratumoral immune balance is inadequate, hindering the optimal desi...

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Detalles Bibliográficos
Autores principales: Nickols, Nicholas G., Ganapathy, Ekambaram, Nguyen, Christine, Kane, Nathanael, Lin, Lin, Diaz-Perez, Silvia, Nazarian, Ramin, Mathis, Colleen, Felix, Care, Basehart, Vince, Zomorodian, Nazy, Kwak, Jae, Kishan, Amar U., King, Christopher R., Kupelian, Patrick A., Rettig, Matthew B., Steinberg, Michael L., Cao, Minsong, Knudsen, Beatrice S., Chu, Fang-I, Romero, Tahmineh, Elashoff, David, Reiter, Robert E., Schaue, Dörthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794088/
https://www.ncbi.nlm.nih.gov/pubmed/32647353
http://dx.doi.org/10.1038/s41391-020-0249-8

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