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Investigating the influence of physiologically relevant hydrostatic pressure on CHO cell batch culture
Chinese hamster ovary (CHO) cells have been the most commonly used mammalian host for large-scale commercial production of therapeutic proteins, such as monoclonal antibodies. Enhancement of productivity of these CHO cells is one of the top priorities in the biopharmaceutical industry to reduce manu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794228/ https://www.ncbi.nlm.nih.gov/pubmed/33420324 http://dx.doi.org/10.1038/s41598-020-80576-8 |