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Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design

HCV vaccine development is stymied by the high genetic diversity of the virus and the variability of the envelope glycoproteins. One strategy to overcome this is to identify conserved, functionally important regions—such as the epitopes of broadly neutralizing antibodies (bNAbs)—and use these as a b...

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Detalles Bibliográficos
Autores principales:	Cowton, Vanessa M., Owsianka, Ania M., Fadda, Valeria, Ortega-Prieto, Ana Maria, Cole, Sarah J., Potter, Jane A., Skelton, Jessica K., Jeffrey, Nathan, Di Lorenzo, Caterina, Dorner, Marcus, Taylor, Garry L., Patel, Arvind H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794244/ https://www.ncbi.nlm.nih.gov/pubmed/33420102 http://dx.doi.org/10.1038/s41541-020-00269-1

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