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Valproic acid-exposed astrocytes impair inhibitory synapse formation and function

Valproic acid (VPA) is widely prescribed to treat epilepsy. Maternal VPA use is, however, clinically restricted because of the severe risk that VPA may cause neurodevelopmental disorders in offspring, such as autism spectrum disorder. Understanding the negative action of VPA may help to prevent VPA-...

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Detalles Bibliográficos
Autores principales:	Takeda, Kotomi, Watanabe, Takuya, Oyabu, Kohei, Tsukamoto, Shuntaro, Oba, Yuki, Nakano, Takafumi, Kubota, Kaori, Katsurabayashi, Shutaro, Iwasaki, Katsunori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794250/ https://www.ncbi.nlm.nih.gov/pubmed/33420078 http://dx.doi.org/10.1038/s41598-020-79520-7

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