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Restoration of surfactant activity by polymyxin B in lipopolysaccharide-potentiated injury of immature rabbit lungs

During postnatal adaptation pulmonary surfactant may be inactivated by lipopolysaccharide (LPS). We evaluated the effect of surfactant therapy in combination with antibiotic polymyxin B (PxB) in double-hit model of neonatal lung injury. Surfactant (poractant alfa, Curosurf) was exposed to smooth (S)...

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Detalles Bibliográficos
Autores principales:	Calkovska, Andrea, Haegerstrand-Björkman, Marie, Curstedt, Tore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794303/ https://www.ncbi.nlm.nih.gov/pubmed/33420141 http://dx.doi.org/10.1038/s41598-020-79679-z

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