Cargando…
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung
Understanding the factors that contribute to efficient SARS-CoV-2 infection of human cells may provide insights on SARS-CoV-2 transmissibility and pathogenesis, and reveal targets of intervention. Here, we analyze host and viral determinants essential for efficient SARS-CoV-2 infection in both human...
Autores principales: | Chu, Hin, Hu, Bingjie, Huang, Xiner, Chai, Yue, Zhou, Dongyan, Wang, Yixin, Shuai, Huiping, Yang, Dong, Hou, Yuxin, Zhang, Xi, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhang, Anna Jinxia, Zhou, Jie, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chan, Ivy Hau-Yee, Sit, Ko-Yung, Foo, Dominic Chi-Chung, Wong, Ian Yu-Hong, Ng, Ada Tsui-Lin, Cheung, Tan To, Law, Simon Ying-Kit, Au, Wing-Kuk, Brindley, Melinda A., Chen, Zhiwei, Kok, Kin-Hang, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794309/ https://www.ncbi.nlm.nih.gov/pubmed/33420022 http://dx.doi.org/10.1038/s41467-020-20457-w |
Ejemplares similares
-
SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19
por: Chu, Hin, et al.
Publicado: (2020) -
Altered host protease determinants for SARS-CoV-2 Omicron
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2023) -
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2
por: Hu, Bingjie, et al.
Publicado: (2022) -
Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer
por: Shuai, Huiping, et al.
Publicado: (2020) -
hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs
por: Zhang, Xi, et al.
Publicado: (2022)