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AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice
Adiponectin receptors, AdipoR1 and AdipoR2 exert anti-diabetic effects. Although muscle-specific disruption of AdipoR1 has been shown to result in decreased insulin sensitivity and decreased exercise endurance, it remains to be determined whether upregulation of AdipoR1 could reverse them in obese d...
Autores principales: | Iwabu, Masato, Okada-Iwabu, Miki, Tanabe, Hiroaki, Ohuchi, Nozomi, Miyata, Keiko, Kobori, Toshiko, Odawara, Sara, Kadowaki, Yuri, Yokoyama, Shigeyuki, Yamauchi, Toshimasa, Kadowaki, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794315/ https://www.ncbi.nlm.nih.gov/pubmed/33420419 http://dx.doi.org/10.1038/s42003-020-01579-9 |
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