Mammalian expression of virus-like particles as a proof of principle for next generation polio vaccines

Global vaccination programs using live-attenuated oral and inactivated polio vaccine (OPV and IPV) have almost eradicated poliovirus (PV) but these vaccines or their production pose significant risk in a polio-free world. Recombinant PV virus-like particles (VLPs), lacking the viral genome, represen...

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Detalles Bibliográficos
Autores principales: Bahar, Mohammad W., Porta, Claudine, Fox, Helen, Macadam, Andrew J., Fry, Elizabeth E., Stuart, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794334/
https://www.ncbi.nlm.nih.gov/pubmed/33420068
http://dx.doi.org/10.1038/s41541-020-00267-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794334/
https://www.ncbi.nlm.nih.gov/pubmed/33420068
http://dx.doi.org/10.1038/s41541-020-00267-3

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