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Structures of human dual oxidase 1 complex in low-calcium and high-calcium states

Dual oxidases (DUOXs) produce hydrogen peroxide by transferring electrons from intracellular NADPH to extracellular oxygen. They are involved in many crucial biological processes and human diseases, especially in thyroid diseases. DUOXs are protein complexes co-assembled from the catalytic DUOX subu...

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Detalles Bibliográficos
Autores principales: Wu, Jing-Xiang, Liu, Rui, Song, Kangcheng, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794343/
https://www.ncbi.nlm.nih.gov/pubmed/33420071
http://dx.doi.org/10.1038/s41467-020-20466-9