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Structures of human dual oxidase 1 complex in low-calcium and high-calcium states
Dual oxidases (DUOXs) produce hydrogen peroxide by transferring electrons from intracellular NADPH to extracellular oxygen. They are involved in many crucial biological processes and human diseases, especially in thyroid diseases. DUOXs are protein complexes co-assembled from the catalytic DUOX subu...
Autores principales: | Wu, Jing-Xiang, Liu, Rui, Song, Kangcheng, Chen, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794343/ https://www.ncbi.nlm.nih.gov/pubmed/33420071 http://dx.doi.org/10.1038/s41467-020-20466-9 |
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