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Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota
The occurrence and spread of multidrug-resistant pathogens, especially bacteria from the ESKAPE panel, increases the risk to succumb to untreatable infections. We developed a novel antimicrobial peptide, Pam-3, with antibacterial and antibiofilm properties to counter this threat. The peptide is base...
Autores principales: | Koeninger, Louis, Osbelt, Lisa, Berscheid, Anne, Wendler, Judith, Berger, Jürgen, Hipp, Katharina, Lesker, Till R., Pils, Marina C., Malek, Nisar P., Jensen, Benjamin A. H., Brötz-Oesterhelt, Heike, Strowig, Till, Jan Wehkamp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794397/ https://www.ncbi.nlm.nih.gov/pubmed/33420317 http://dx.doi.org/10.1038/s42003-020-01582-0 |
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