Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage

Pertussis has made a spectacular rebound in countries that have switched from whole-cell (wPV) to acellular pertussis vaccines (aPV). Here, we show that, unlike wPV, aPV, while protective against lung colonization by Bordetella pertussis (Bp), did not protect BALB/c mice from nasal colonization, but...

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Detalles Bibliográficos
Autores principales: Dubois, Violaine, Chatagnon, Jonathan, Thiriard, Anaïs, Bauderlique-Le Roy, Hélène, Debrie, Anne-Sophie, Coutte, Loïc, Locht, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794405/
https://www.ncbi.nlm.nih.gov/pubmed/33420041
http://dx.doi.org/10.1038/s41541-020-00270-8

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