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Time-resolved non-invasive metabolomic monitoring of a single cancer spheroid by microfluidic NMR

We present a quantitative study of the metabolic activity of a single spheroid culture of human cancer cells. NMR (nuclear magnetic resonance) spectroscopy is an ideal tool for observation of live systems due to its non-invasive nature. However, limited sensitivity has so far hindered its applicatio...

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Detalles Bibliográficos
Autores principales: Patra, Bishnubrata, Sharma, Manvendra, Hale, William, Utz, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794408/
https://www.ncbi.nlm.nih.gov/pubmed/33420162
http://dx.doi.org/10.1038/s41598-020-79693-1