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Time-resolved non-invasive metabolomic monitoring of a single cancer spheroid by microfluidic NMR
We present a quantitative study of the metabolic activity of a single spheroid culture of human cancer cells. NMR (nuclear magnetic resonance) spectroscopy is an ideal tool for observation of live systems due to its non-invasive nature. However, limited sensitivity has so far hindered its applicatio...
Autores principales: | Patra, Bishnubrata, Sharma, Manvendra, Hale, William, Utz, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794408/ https://www.ncbi.nlm.nih.gov/pubmed/33420162 http://dx.doi.org/10.1038/s41598-020-79693-1 |
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