GluN2B and GluN2A-containing NMDAR are differentially involved in extinction memory destabilization and restabilization during reconsolidation

Extinction memory destabilized by recall is restabilized through mTOR-dependent reconsolidation in the hippocampus, but the upstream pathways controlling these processes remain unknown. Hippocampal NMDARs drive local protein synthesis via mTOR signaling and may control active memory maintenance. We...

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Detalles Bibliográficos
Autores principales: Radiske, Andressa, Gonzalez, Maria Carolina, Nôga, Diana A., Rossato, Janine I., Bevilaqua, Lia R. M., Cammarota, Martín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794413/
https://www.ncbi.nlm.nih.gov/pubmed/33420399
http://dx.doi.org/10.1038/s41598-020-80674-7

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