A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer

In this research, dispersion of a new type of one-dimensional inorganic material Nb(2)Se(9), composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb(2)Se(9), which exhibits hydrophobic properties in water, experiments were carried out using a block...

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Autores principales: Chae, Sudong, Oh, Seungbae, Choi, Kyung Hwan, Lee, Jin Woong, Jeon, Jiho, Liu, Zhixiang, Wang, Cong, Lim, Changmo, Dong, Xue, Woo, Chaeheon, Asghar, Ghulam, Shi, Liyi, Kang, Joohoon, Kim, Sung Jae, Song, Si Young, Lee, Jung Heon, Yu, Hak Ki, Choi, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794490/
https://www.ncbi.nlm.nih.gov/pubmed/33420413
http://dx.doi.org/10.1038/s41598-020-80730-2
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author Chae, Sudong
Oh, Seungbae
Choi, Kyung Hwan
Lee, Jin Woong
Jeon, Jiho
Liu, Zhixiang
Wang, Cong
Lim, Changmo
Dong, Xue
Woo, Chaeheon
Asghar, Ghulam
Shi, Liyi
Kang, Joohoon
Kim, Sung Jae
Song, Si Young
Lee, Jung Heon
Yu, Hak Ki
Choi, Jae-Young
author_facet Chae, Sudong
Oh, Seungbae
Choi, Kyung Hwan
Lee, Jin Woong
Jeon, Jiho
Liu, Zhixiang
Wang, Cong
Lim, Changmo
Dong, Xue
Woo, Chaeheon
Asghar, Ghulam
Shi, Liyi
Kang, Joohoon
Kim, Sung Jae
Song, Si Young
Lee, Jung Heon
Yu, Hak Ki
Choi, Jae-Young
author_sort Chae, Sudong
collection PubMed
description In this research, dispersion of a new type of one-dimensional inorganic material Nb(2)Se(9), composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb(2)Se(9), which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb(2)Se(9), and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb(2)Se(9) to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb(2)Se(9) using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.
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spelling pubmed-77944902021-01-12 A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer Chae, Sudong Oh, Seungbae Choi, Kyung Hwan Lee, Jin Woong Jeon, Jiho Liu, Zhixiang Wang, Cong Lim, Changmo Dong, Xue Woo, Chaeheon Asghar, Ghulam Shi, Liyi Kang, Joohoon Kim, Sung Jae Song, Si Young Lee, Jung Heon Yu, Hak Ki Choi, Jae-Young Sci Rep Article In this research, dispersion of a new type of one-dimensional inorganic material Nb(2)Se(9), composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb(2)Se(9), which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb(2)Se(9), and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb(2)Se(9) to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb(2)Se(9) using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells. Nature Publishing Group UK 2021-01-08 /pmc/articles/PMC7794490/ /pubmed/33420413 http://dx.doi.org/10.1038/s41598-020-80730-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Chae, Sudong
Oh, Seungbae
Choi, Kyung Hwan
Lee, Jin Woong
Jeon, Jiho
Liu, Zhixiang
Wang, Cong
Lim, Changmo
Dong, Xue
Woo, Chaeheon
Asghar, Ghulam
Shi, Liyi
Kang, Joohoon
Kim, Sung Jae
Song, Si Young
Lee, Jung Heon
Yu, Hak Ki
Choi, Jae-Young
A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title_full A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title_fullStr A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title_full_unstemmed A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title_short A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb(2)Se(9) using poloxamer
title_sort study on the bio-applicability of aqueous-dispersed van der waals 1-d material nb(2)se(9) using poloxamer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794490/
https://www.ncbi.nlm.nih.gov/pubmed/33420413
http://dx.doi.org/10.1038/s41598-020-80730-2
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