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Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aβ fibrils

Alzheimer’s disease is characterized by neuritic plaques, the main protein components of which are β-amyloid (Aβ) peptides deposited as β-sheet-rich amyloid fibrils. Cerebral Amyloid Angiopathy (CAA) consists of cerebrovascular deposits of Aβ peptides; it usually accompanies Alzheimer’s disease, tho...

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Detalles Bibliográficos
Autores principales:	Scherpelz, Kathryn P., Wang, Songlin, Pytel, Peter, Madhurapantula, Rama S., Srivastava, Atul K., Sachleben, Joseph R., Orgel, Joseph, Ishii, Yoshitaka, Meredith, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794565/ https://www.ncbi.nlm.nih.gov/pubmed/33420184 http://dx.doi.org/10.1038/s41598-020-80042-5

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