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Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection
The RNA interference (RNAi) drug ARC-520 was shown to be effective in reducing serum hepatitis B virus (HBV) DNA, hepatitis B e antigen (HBeAg) and hepatitis B surface antigen (HBsAg) in HBeAg-positive patients treated with a single dose of ARC-520 and daily nucleosidic analogue (entecavir). To prov...
Autores principales: | Kadelka, Sarah, Dahari, Harel, Ciupe, Stanca M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794570/ https://www.ncbi.nlm.nih.gov/pubmed/33420293 http://dx.doi.org/10.1038/s41598-020-80594-6 |
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