Cargando…

Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy

The use of pesticides to reduce mosquito vector populations is a cornerstone of global malaria control efforts, but the biological impact of most pesticides on human populations, including pregnant women and infants, is not known. Some pesticides, including carbamates, have been shown to perturb the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prahl, Mary, Odorizzi, Pamela, Gingrich, David, Muhindo, Mary, McIntyre, Tara, Budker, Rachel, Jagannathan, Prasanna, Farrington, Lila, Nalubega, Mayimuna, Nankya, Felistas, Sikyomu, Esther, Musinguzi, Kenneth, Naluwu, Kate, Auma, Ann, Kakuru, Abel, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Feeney, Margaret E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794579/ https://www.ncbi.nlm.nih.gov/pubmed/33420104 http://dx.doi.org/10.1038/s41467-020-20475-8

Ejemplares similares

Sex Disparity in Cord Blood FoxP3(+) CD4 T Regulatory Cells in Infants Exposed to Malaria In Utero
por: Prahl, Mary, et al.
Publicado: (2017)

Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation
por: Prahl, Mary, et al.
Publicado: (2016)

Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure
por: Jagannathan, Prasanna, et al.
Publicado: (2017)

Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure
por: Farrington, Lila A., et al.
Publicado: (2020)

In Utero Activation of Natural Killer Cells in Congenital Cytomegalovirus Infection
por: Vaaben, Anna V, et al.
Publicado: (2022)

Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria
por: Boyle, Michelle J., et al.
Publicado: (2015)

The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission
por: Boyle, Michelle J., et al.
Publicado: (2017)

Age-Related Changes in Malaria Clinical Phenotypes During Infancy Are Modified by Sickle Cell Trait
por: Zehner, Nicholas, et al.
Publicado: (2021)

IFNγ/IL-10 Co-producing Cells Dominate the CD4 Response to Malaria in Highly Exposed Children
por: Jagannathan, Prasanna, et al.
Publicado: (2014)

Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial
por: Jagannathan, Prasanna, et al.
Publicado: (2018)

Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malaria
por: Kirosingh, Adam S., et al.
Publicado: (2023)

Erratum to: B cell sub-types following acute malaria and associations with clinical immunity
por: Sullivan, Richard T., et al.
Publicado: (2016)

Both inflammatory and regulatory cytokine responses to malaria are blunted with increasing age in highly exposed children
por: Farrington, Lila, et al.
Publicado: (2017)

Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children
por: Sundell, Kerstin, et al.
Publicado: (2015)

Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children
por: Wallender, Erika, et al.
Publicado: (2021)

B cell sub-types following acute malaria and associations with clinical immunity
por: Sullivan, Richard T., et al.
Publicado: (2016)

Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children
por: Chan, Jo-Anne, et al.
Publicado: (2022)

Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
por: Jagannathan, Prasanna, et al.
Publicado: (2012)

Early parasite clearance following artemisinin-based combination therapy among Ugandan children with uncomplicated Plasmodium falciparum malaria
por: Muhindo, Mary K, et al.
Publicado: (2014)

Generation of a malaria negative Ugandan birth weight standard for the diagnosis of small for gestational age
por: Zakama, Arthurine K., et al.
Publicado: (2020)

Infant sex modifies associations between placental malaria and risk of malaria in infancy
por: Kakuru, Abel, et al.
Publicado: (2020)

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure
por: Sullivan, Richard T., et al.
Publicado: (2015)

Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting
por: Kakuru, Abel, et al.
Publicado: (2016)

Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: a randomized controlled trial
por: Kakuru, Abel, et al.
Publicado: (2020)

The impact of gravidity, symptomatology and timing of infection on placental malaria
por: Tran, Erin E., et al.
Publicado: (2020)

Reductions in malaria in pregnancy and adverse birth outcomes following indoor residual spraying of insecticide in Uganda
por: Muhindo, Mary K., et al.
Publicado: (2016)

T-follicular helper cells in malaria infection and roles in antibody induction
por: Soon, Megan S F, et al.
Publicado: (2021)

The Impact of Control Interventions on Malaria Burden in Young Children in a Historically High-Transmission District of Uganda: A Pooled Analysis of Cohort Studies from 2007 to 2018
por: Kamya, Moses R., et al.
Publicado: (2020)

Relationships between infection with Plasmodium falciparum during pregnancy, measures of placental malaria, and adverse birth outcomes
por: Kapisi, James, et al.
Publicado: (2017)

Protective Efficacy and Safety of Three Antimalarial Regimens for the Prevention of Malaria in Young Ugandan Children: A Randomized Controlled Trial
por: Bigira, Victor, et al.
Publicado: (2014)

B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells
por: Braddom, Ashley E., et al.
Publicado: (2021)

Polymorphisms in K13 and Falcipain-2 Associated with Artemisinin Resistance Are Not Prevalent in Plasmodium falciparum Isolated from Ugandan Children
por: Conrad, Melissa D., et al.
Publicado: (2014)

The utilization of clinical decision support tools to identify neonatal hypothermia and its associated risk factors: A prospective observational study
por: Muhindo, Mary Kakuru, et al.
Publicado: (2023)

Malaria in 2022: Increasing challenges, cautious optimism
por: Jagannathan, Prasanna, et al.
Publicado: (2022)

Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria
por: Tchaparian, Eskouhie, et al.
Publicado: (2016)

An Investigation into Pyuria in Infancy and Childhood
por: Griffin, Mary A.
Publicado: (1930)

The prevalence of histologic acute chorioamnionitis among HIV infected pregnant women in Uganda and its association with adverse birth outcomes
por: Ategeka, John, et al.
Publicado: (2019)

Gravidity-dependent associations between interferon response and birth weight in placental malaria
por: Quanquin, Natalie M., et al.
Publicado: (2020)

Assessment of the fetal lungs in utero
por: Avena-Zampieri, Carla L., et al.
Publicado: (2022)

In utero Undernutrition Programs Skeletal and Cardiac Muscle Metabolism
por: Beauchamp, Brittany, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4dkl1btqqllej1eg2bop6ibcna