Cargando…
Prognostic gene expression signatures of breast cancer are lacking a sensible biological meaning
The identification of prognostic biomarkers for predicting cancer progression is an important problem for two reasons. First, such biomarkers find practical application in a clinical context for the treatment of patients. Second, interrogation of the biomarkers themselves is assumed to lead to novel...
Autores principales: | Manjang, Kalifa, Tripathi, Shailesh, Yli-Harja, Olli, Dehmer, Matthias, Glazko, Galina, Emmert-Streib, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794581/ https://www.ncbi.nlm.nih.gov/pubmed/33420139 http://dx.doi.org/10.1038/s41598-020-79375-y |
Ejemplares similares
-
Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures
por: Emmert-Streib, Frank, et al.
Publicado: (2021) -
Graph-based exploitation of gene ontology using GOxploreR for scrutinizing biological significance
por: Manjang, Kalifa, et al.
Publicado: (2020) -
Limitations of Explainability for Established Prognostic Biomarkers of Prostate Cancer
por: Manjang, Kalifa, et al.
Publicado: (2021) -
Against Dataism and for Data Sharing of Big Biomedical and Clinical Data with Research Parasites
por: Emmert-Streib, Frank, et al.
Publicado: (2016) -
Lessons from the Human Genome Project: Modesty, Honesty, and Realism
por: Emmert-Streib, Frank, et al.
Publicado: (2017)