Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis

N-glycosylation is instrumental to the regulation of CD147 functions, including the maturation of CD147, secretion of matrix metalloproteinases (MMPs), and promotion of tumor metastasis. Glycosylated CD147 is highly expressed in various cancer types, participates in metastasis, and is associated wit...

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Detalles Bibliográficos
Autores principales: Li, Wenqian, Wang, Daojiong, Ge, Yushu, Zhang, Lei, Wu, Jiang, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794696/
https://www.ncbi.nlm.nih.gov/pubmed/33374805
http://dx.doi.org/10.3390/molecules26010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794696/
https://www.ncbi.nlm.nih.gov/pubmed/33374805
http://dx.doi.org/10.3390/molecules26010033

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