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Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study

Given the rising rate of opioid-related adverse drug events during postsurgical pain management, a nonpharmacologic therapy that could decrease analgesic medication requirements would be of immense value. We designed a prospective, placebo-and-randomized controlled trial to assess the clinical effec...

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Autores principales: Szmit, Mateusz, Agrawal, Siddarth, Goździk, Waldemar, Kübler, Andrzej, Agrawal, Anil, Pruchnicki, Piotr, Woźniak, Marta, Nowak, Matylda, Bartoszewicz, Bartłomiej, Rudnicki, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794768/
https://www.ncbi.nlm.nih.gov/pubmed/33406735
http://dx.doi.org/10.3390/jcm10010146
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author Szmit, Mateusz
Agrawal, Siddarth
Goździk, Waldemar
Kübler, Andrzej
Agrawal, Anil
Pruchnicki, Piotr
Woźniak, Marta
Nowak, Matylda
Bartoszewicz, Bartłomiej
Rudnicki, Jerzy
author_facet Szmit, Mateusz
Agrawal, Siddarth
Goździk, Waldemar
Kübler, Andrzej
Agrawal, Anil
Pruchnicki, Piotr
Woźniak, Marta
Nowak, Matylda
Bartoszewicz, Bartłomiej
Rudnicki, Jerzy
author_sort Szmit, Mateusz
collection PubMed
description Given the rising rate of opioid-related adverse drug events during postsurgical pain management, a nonpharmacologic therapy that could decrease analgesic medication requirements would be of immense value. We designed a prospective, placebo-and-randomized controlled trial to assess the clinical effect of transcutaneous acupoint electrical stimulation (TEAS) on the postoperative patient-controlled analgesia (PCA) requirement for morphine, as well as side effects and recovery profile after inguinal hernia repair. Seventy-one subjects undergoing inguinal hernia repair with a standardized anesthetic technique were randomly assigned to one of three analgesic treatment regimens: PCA + TEAS (n = 24); PCA + sham-TEAS (no electrical stimulation) (n = 24), and PCA only (n = 23). The postoperative PCA requirement, pain scores, opioid-related side effects, and blood cortisol levels were recorded. TEAS treatment resulted in a twofold decrease in the analgesic requirement and decreased pain level reported by the patients. In addition, a significant reduction of cortisol level was reported in the TEAS group at 24 h postoperatively compared to the sham and control groups. We conclude that TEAS is a safe and effective option for reducing analgesic consumption and postoperative pain following inguinal hernia repair.
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spelling pubmed-77947682021-01-10 Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study Szmit, Mateusz Agrawal, Siddarth Goździk, Waldemar Kübler, Andrzej Agrawal, Anil Pruchnicki, Piotr Woźniak, Marta Nowak, Matylda Bartoszewicz, Bartłomiej Rudnicki, Jerzy J Clin Med Article Given the rising rate of opioid-related adverse drug events during postsurgical pain management, a nonpharmacologic therapy that could decrease analgesic medication requirements would be of immense value. We designed a prospective, placebo-and-randomized controlled trial to assess the clinical effect of transcutaneous acupoint electrical stimulation (TEAS) on the postoperative patient-controlled analgesia (PCA) requirement for morphine, as well as side effects and recovery profile after inguinal hernia repair. Seventy-one subjects undergoing inguinal hernia repair with a standardized anesthetic technique were randomly assigned to one of three analgesic treatment regimens: PCA + TEAS (n = 24); PCA + sham-TEAS (no electrical stimulation) (n = 24), and PCA only (n = 23). The postoperative PCA requirement, pain scores, opioid-related side effects, and blood cortisol levels were recorded. TEAS treatment resulted in a twofold decrease in the analgesic requirement and decreased pain level reported by the patients. In addition, a significant reduction of cortisol level was reported in the TEAS group at 24 h postoperatively compared to the sham and control groups. We conclude that TEAS is a safe and effective option for reducing analgesic consumption and postoperative pain following inguinal hernia repair. MDPI 2021-01-04 /pmc/articles/PMC7794768/ /pubmed/33406735 http://dx.doi.org/10.3390/jcm10010146 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Szmit, Mateusz
Agrawal, Siddarth
Goździk, Waldemar
Kübler, Andrzej
Agrawal, Anil
Pruchnicki, Piotr
Woźniak, Marta
Nowak, Matylda
Bartoszewicz, Bartłomiej
Rudnicki, Jerzy
Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title_full Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title_fullStr Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title_full_unstemmed Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title_short Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study
title_sort transcutaneous electrical acupoint stimulation reduces postoperative analgesic requirement in patients undergoing inguinal hernia repair: a randomized, placebo-controlled study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794768/
https://www.ncbi.nlm.nih.gov/pubmed/33406735
http://dx.doi.org/10.3390/jcm10010146
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