Cargando…

Analysis of the TCGA Dataset Reveals that Subsites of Laryngeal Squamous Cell Carcinoma Are Molecularly Distinct

SIMPLE SUMMARY: Squamous cell carcinomas from different parts of the larynx have distinct presentations and prognoses, but the molecular basis for this discrepancy has yet to be characterized. We aimed to determine whether different types of mutations at the DNA, mRNA, and protein levels exist to ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sorgini, Alana, Kim, Hugh Andrew Jinwook, Zeng, Peter Y. F., Shaikh, Mushfiq Hassan, Mundi, Neil, Ghasemi, Farhad, Di Gravio, Eric, Khan, Halema, MacNeil, Danielle, Khan, Mohammed Imran, Mendez, Adrian, Yoo, John, Fung, Kevin, Lang, Pencilla, Palma, David A., Mymryk, Joe S., Barrett, John W., Patel, Krupal B., Boutros, Paul C., Nichols, Anthony C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794818/ https://www.ncbi.nlm.nih.gov/pubmed/33396315 http://dx.doi.org/10.3390/cancers13010105

Ejemplares similares

3p Arm Loss and Survival in Head and Neck Cancer: An Analysis of TCGA Dataset
por: Kim, Hugh Andrew Jinwook, et al.
Publicado: (2021)

Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models
por: Pinto, Nicole, et al.
Publicado: (2020)

Modern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution
por: Di Gravio, Eric J., et al.
Publicado: (2020)

Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival
por: Mundi, Neil, et al.
Publicado: (2019)

Introduction and expression of PIK3CA(E545K) in a papillary thyroid cancer BRAF(V600E) cell line leads to a dedifferentiated aggressive phenotype
por: Pinto, Nicole, et al.
Publicado: (2022)

Laryngeal Subsite Analysis of Granulomatosis With Polyangiitis (Wegener’s)
por: Minaya, Natasha J., et al.
Publicado: (2021)

Does HPV Subtype Predict Outcomes in Head and Neck Cancers?
por: Ziai, Hedyeh, et al.
Publicado: (2021)

Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
por: Gameiro, Steven F., et al.
Publicado: (2021)

Concordance between head and neck MRI and histopathology in detecting laryngeal subsite invasion among patients with laryngeal cancer
por: Mohamad, Issa, et al.
Publicado: (2023)

Treatment of early stage Supraglottic squamous cell carcinoma: meta-analysis comparing primary surgery versus primary radiotherapy
por: Patel, Krupal B., et al.
Publicado: (2018)

Functional outcomes in early (T1/T2) supraglottic cancer: a systematic review
por: van der Woerd, Benjamin, et al.
Publicado: (2018)

High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines
por: Ghasemi, Farhad, et al.
Publicado: (2018)

Genomically Driven Precision Medicine to Improve Outcomes in Anaplastic Thyroid Cancer
por: Pinto, Nicole, et al.
Publicado: (2014)

High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells
por: Gameiro, Steven F., et al.
Publicado: (2019)

Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification
por: Zeng, Peter Y.F., et al.
Publicado: (2022)

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer
por: Ghasemi, Farhad, et al.
Publicado: (2017)

Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection
por: Gameiro, Steven F., et al.
Publicado: (2017)

Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome
por: Tessier, Tanner M., et al.
Publicado: (2020)

TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
por: Ruicci, Kara M., et al.
Publicado: (2020)

Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
por: Gameiro, Steven F., et al.
Publicado: (2018)

Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Incidence pattern of colorectal cancer in Korea by subsite of origin.
por: Kim, D. H., et al.
Publicado: (2000)

Mandibular Ramus Fracture: An Overview of Rare Anatomical Subsite
por: Jadhav, Anendd, et al.
Publicado: (2015)

Mathematical model for preoperative identification of obstructed nasal subsites
por: Gamerra, M., et al.
Publicado: (2017)

Lestaurtinib is a potent inhibitor of anaplastic thyroid cancer cell line models
por: Pinto, Nicole, et al.
Publicado: (2018)

Different age and sex relationship for cancer of subsites of the large bowel.
por: Jensen, O. M.
Publicado: (1984)

Acid-suppressing therapies and subsite-specific risk of stomach cancer
por: Wennerström, E Christina M, et al.
Publicado: (2017)

Muonium Chemistry at Diiron Subsite Analogues of [FeFe]‐Hydrogenase
por: Wright, Joseph A., et al.
Publicado: (2016)

Smoking-Related Risks of Colorectal Cancer by Anatomical Subsite and Sex
por: Gram, Inger T, et al.
Publicado: (2020)

Endoscopic landmarks corresponding to anatomical landmarks for esophageal subsite classification
por: Ishihara, Ryu, et al.
Publicado: (2023)

Anthropometry, body fat composition and reproductive factors and risk of oesophageal and gastric cancer by subtype and subsite in the UK Biobank cohort
por: Sanikini, Harinakshi, et al.
Publicado: (2020)

Subsite Distribution of Gastric Cancer in an Area of High Prevalence—Northwest Iran
por: Bafandeh, Yousef, et al.
Publicado: (2009)

Subsite (cervix/endometrium)‐specific Risk and Protective Factors in Uterus Cancer
por: Hirose, Kaoru, et al.
Publicado: (1996)

The Immune Microenvironment in Head and Neck Squamous Cell Carcinoma: on Subsets and Subsites
por: Wondergem, Niels E., et al.
Publicado: (2020)

Circulating hormones and risk of gastric cancer by subsite in three cohort studies
por: Sanikini, Harinakshi, et al.
Publicado: (2023)

Association between Tumor Microbiome and Hypoxia across Anatomic Subsites of Head and Neck Cancers
por: Dhakal, Aastha, et al.
Publicado: (2022)

TCGA Expedition: A Data Acquisition and Management System for TCGA Data
por: Chandran, Uma R., et al.
Publicado: (2016)

Exploring Multi‐Subsite Binding Pockets in Proteins: DEEP‐STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B
por: Monaco, Serena, et al.
Publicado: (2020)

Establishment of four head and neck squamous cell carcinoma cell lines: importance of reference DNA for accurate genomic characterisation
por: Patel, K B, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9vpt870t01me69e6lhrn2qga76