Cargando…

In Vivo Optical Metabolic Imaging of Long-Chain Fatty Acid Uptake in Orthotopic Models of Triple-Negative Breast Cancer

SIMPLE SUMMARY: A dysregulated metabolism is a hallmark of cancer. Once understood, tumor metabolic reprogramming can lead to targetable vulnerabilities, spurring the development of novel treatment strategies. Beyond the common observation that tumors rely heavily on glucose, building evidence indic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Madonna, Megan C., Duer, Joy E., Lee, Joyce V., Williams, Jeremy, Avsaroglu, Baris, Zhu, Caigang, Deutsch, Riley, Wang, Roujia, Crouch, Brian T., Hirschey, Matthew D., Goga, Andrei, Ramanujam, Nirmala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794847/ https://www.ncbi.nlm.nih.gov/pubmed/33466329 http://dx.doi.org/10.3390/cancers13010148

Ejemplares similares

Adaptive Design of Fluorescence Imaging Systems for Custom Resolution, Fields of View, and Geometries
por: Wang, Roujia, et al.
Publicado: (2023)

In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence
por: Madonna, Megan C., et al.
Publicado: (2022)

Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer
por: Crouch, Brian T., et al.
Publicado: (2019)

A Spectroscopic Technique to Simultaneously Characterize Fatty Acid Uptake, Mitochondrial Activity, Vascularity, and Oxygen Saturation for Longitudinal Studies In Vivo
por: Deutsch, Riley J., et al.
Publicado: (2022)

Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer
por: Zhu, Caigang, et al.
Publicado: (2017)

Targeting Tumor Acidosis and Regulatory T Cells Unmasks Anti-Metastatic Potential of Local Tumor Ablation in Triple-Negative Breast Cancer
por: Nief, Corrine A., et al.
Publicado: (2022)

Non-Invasive, Simultaneous Quantification of Vascular Oxygenation and Glucose Uptake in Tissue
por: Rajaram, Narasimhan, et al.
Publicado: (2015)

Multicontrast Pocket Colposcopy Cervical Cancer Diagnostic Algorithm for Referral Populations
por: Skerrett, Erica, et al.
Publicado: (2022)

Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model
por: Oizel, Kristell, et al.
Publicado: (2020)

Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging
por: Martinez, Amy F., et al.
Publicado: (2018)

Development of enhanced ethanol ablation as an alternative to surgery in treatment of superficial solid tumors
por: Morhard, Robert, et al.
Publicado: (2017)

Radiologic-pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose
por: Chelales, Erika, et al.
Publicado: (2021)

Delivery Rate Affects Uptake of a Fluorescent Glucose Analog in Murine Metastatic Breast Cancer
por: Rajaram, Narasimhan, et al.
Publicado: (2013)

Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer
por: Echeverria, Gloria V., et al.
Publicado: (2023)

New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer
por: Han, Ye, et al.
Publicado: (2020)

Ethanol Ablation Therapy Drives Immune-Mediated Antitumor Effects in Murine Breast Cancer Models
por: Nief, Corrine A., et al.
Publicado: (2022)

Enzyme inhibition of dopamine metabolism alters 6-[(18)F]FDOPA uptake in orthotopic pancreatic adenocarcinoma
por: Tuomela, Johanna, et al.
Publicado: (2013)

Effect of Chromosome Tethering on Nuclear Organization in Yeast
por: Avşaroğlu, Barış, et al.
Publicado: (2014)

Spatio-Temporal Differences in Economic Security of the Prefecture-Level Cities in Qinghai–Tibet Plateau Region of China: Based on a Triple-Dimension Analytical Framework of Economic Geography
por: Zhu, Huasheng, et al.
Publicado: (2022)

Orthotopic neobladder reconstruction
por: Chang, Dwayne T. S., et al.
Publicado: (2015)

BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer
por: JIANG, JIAHUA, et al.
Publicado: (2012)

Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer
por: Ramani, Vishnu C., et al.
Publicado: (2019)

Adiponectin‐expressing Treg‐containing T cell fraction inhibits tumor growth in orthotopically implanted triple‐negative breast cancer
por: Chikaishi, Wakana, et al.
Publicado: (2023)

Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens
por: Crouch, Brian, et al.
Publicado: (2017)

[(18)F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo
por: Solingapuram Sai, Kiran Kumar, et al.
Publicado: (2021)

Seroprevalence of Rodent Pathogens in Wild Rats from the Island of St. Kitts, West Indies
por: Boey, Kenneth, et al.
Publicado: (2019)

SYST-31 PROBIOTIC DELIVERY TO ORTHOTOPIC GLIOBLASTOMA MULTIFORME MODELS AS AN IMMUNOTHERAPY
por: Windemuth, Sophia, et al.
Publicado: (2023)

Orthotopic Liver Transplantation in Rats
por: Oldani, Graziano, et al.
Publicado: (2012)

LIPH promotes metastasis by enriching stem‐like cells in triple‐negative breast cancer
por: Zhang, Yixiao, et al.
Publicado: (2020)

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
por: Camarda, Roman, et al.
Publicado: (2016)

Prognostic significance of GSTP1 in patients with triple negative breast cancer
por: Chen, Guanglei, et al.
Publicado: (2017)

Multimodality Imaging Methods for Assessing Retinoblastoma Orthotopic Xenograft Growth and Development
por: Corson, Timothy W., et al.
Publicado: (2014)

Hydroxyproline Ring Pucker Causes Frustration of Helix Parameters in the Collagen Triple Helix
por: Ying Chow, W., et al.
Publicado: (2015)

Tech stock valuation: investor psychology and economic analysis
por: Hirschey, Mark
Publicado: (2003)

P700: THE MECHANISM OF SETD2 IN MESENCHYMAL STEM CELLS REGULATED UBA5 IN MDS ERYTHROID DIFFERENTIATION
por: Wang, Roujia, et al.
Publicado: (2023)

Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model
por: Buraschi, Simone, et al.
Publicado: (2012)

Therapeutic impact of Nintedanib with paclitaxel and/or a PD-L1 antibody in preclinical models of orthotopic primary or metastatic triple negative breast cancer
por: Reguera-Nuñez, Elaine, et al.
Publicado: (2019)

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2016)

Infections Following Orthotopic Liver Transplantation
por: Arnow, Paul M.
Publicado: (1991)

Orthotopic and heterotopic ovarian tissue transplantation
por: Demeestere, I., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_bng7ro2cvhmj2g3msf7jsi6bko