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Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2(−/−)/Il10(−/−) Mouse Model

Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA methylome, hydroxymethylome, and transcriptome analyses were conducted in proximal colon tissues harvested from the Helic...

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Detalles Bibliográficos
Autores principales:	Han, Qiyuan, Kono, Thomas J. Y., Knutson, Charles G., Parry, Nicola M., Seiler, Christopher L., Fox, James G., Tannenbaum, Steven R., Tretyakova, Natalia Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795000/ https://www.ncbi.nlm.nih.gov/pubmed/33396408 http://dx.doi.org/10.3390/ijms22010364

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