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Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unus...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795071/ https://www.ncbi.nlm.nih.gov/pubmed/33383815 http://dx.doi.org/10.3390/s21010170 |
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author | Khelifa, Meriam Mounier, Denis Yaakoubi, Nourdin |
author_facet | Khelifa, Meriam Mounier, Denis Yaakoubi, Nourdin |
author_sort | Khelifa, Meriam |
collection | PubMed |
description | The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unusual proximity effect favours optimised scroll microcoils with a large number of turns rolled up in close proximity. Scroll microcoils have many advantages over microsolenoids: such as ease of fabrication and better [Formula: see text]-homogeneity for comparable intrinsic signal-to-noise ratio (SNR). Scroll coils are suitable for broadband multinuclei NMR spectroscopy of subnanoliter sample. |
format | Online Article Text |
id | pubmed-7795071 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77950712021-01-10 Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples Khelifa, Meriam Mounier, Denis Yaakoubi, Nourdin Sensors (Basel) Article The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unusual proximity effect favours optimised scroll microcoils with a large number of turns rolled up in close proximity. Scroll microcoils have many advantages over microsolenoids: such as ease of fabrication and better [Formula: see text]-homogeneity for comparable intrinsic signal-to-noise ratio (SNR). Scroll coils are suitable for broadband multinuclei NMR spectroscopy of subnanoliter sample. MDPI 2020-12-29 /pmc/articles/PMC7795071/ /pubmed/33383815 http://dx.doi.org/10.3390/s21010170 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Khelifa, Meriam Mounier, Denis Yaakoubi, Nourdin Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title | Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title_full | Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title_fullStr | Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title_full_unstemmed | Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title_short | Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples |
title_sort | design of high performance scroll microcoils for nuclear magnetic resonance spectroscopy of nanoliter and subnanoliter samples |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795071/ https://www.ncbi.nlm.nih.gov/pubmed/33383815 http://dx.doi.org/10.3390/s21010170 |
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