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Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples

The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unus...

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Autores principales: Khelifa, Meriam, Mounier, Denis, Yaakoubi, Nourdin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795071/
https://www.ncbi.nlm.nih.gov/pubmed/33383815
http://dx.doi.org/10.3390/s21010170
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author Khelifa, Meriam
Mounier, Denis
Yaakoubi, Nourdin
author_facet Khelifa, Meriam
Mounier, Denis
Yaakoubi, Nourdin
author_sort Khelifa, Meriam
collection PubMed
description The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unusual proximity effect favours optimised scroll microcoils with a large number of turns rolled up in close proximity. Scroll microcoils have many advantages over microsolenoids: such as ease of fabrication and better [Formula: see text]-homogeneity for comparable intrinsic signal-to-noise ratio (SNR). Scroll coils are suitable for broadband multinuclei NMR spectroscopy of subnanoliter sample.
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spelling pubmed-77950712021-01-10 Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples Khelifa, Meriam Mounier, Denis Yaakoubi, Nourdin Sensors (Basel) Article The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unusual proximity effect favours optimised scroll microcoils with a large number of turns rolled up in close proximity. Scroll microcoils have many advantages over microsolenoids: such as ease of fabrication and better [Formula: see text]-homogeneity for comparable intrinsic signal-to-noise ratio (SNR). Scroll coils are suitable for broadband multinuclei NMR spectroscopy of subnanoliter sample. MDPI 2020-12-29 /pmc/articles/PMC7795071/ /pubmed/33383815 http://dx.doi.org/10.3390/s21010170 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Khelifa, Meriam
Mounier, Denis
Yaakoubi, Nourdin
Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title_full Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title_fullStr Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title_full_unstemmed Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title_short Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples
title_sort design of high performance scroll microcoils for nuclear magnetic resonance spectroscopy of nanoliter and subnanoliter samples
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795071/
https://www.ncbi.nlm.nih.gov/pubmed/33383815
http://dx.doi.org/10.3390/s21010170
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