Cargando…

Loss of Tid1/DNAJA3 Co-Chaperone Promotes Progression and Recurrence of Hepatocellular Carcinoma after Surgical Resection: A Novel Model to Stratify Risk of Recurrence

SIMPLE SUMMARY: Tid1 acts as a tumor suppressor in various cancer types, however, its role in hepatocellular carcinoma (HCC) remains unclear. Here, we observed a low protein level of Tid1 in poorly differentiated HCC cell lines. The expression of Tid1 affected the malignancy in human HCC cell lines;...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Kuan-Yang, Huang, Yi-Hsiang, Teo, Wan-Huai, Chang, Ching-Wen, Chen, Yu-Syuan, Yeh, Yi-Chen, Lee, Chieh-Ju, Lo, Jeng-Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795123/ https://www.ncbi.nlm.nih.gov/pubmed/33406664 http://dx.doi.org/10.3390/cancers13010138

Ejemplares similares

DNAJA3/Tid1 Is Required for Mitochondrial DNA Maintenance and Regulates Migration and Invasion of Human Gastric Cancer Cells
por: Wang, Sheng-Fan, et al.
Publicado: (2020)

Structural resemblance of the DNAJA-family protein, Tid1, to the DNAJB-family Hsp40
por: Jang, Jinhwa, et al.
Publicado: (2022)

HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling
por: Chen, Yu-Syuan, et al.
Publicado: (2018)

Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis
por: Cheng, Li-Hao, et al.
Publicado: (2016)

Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation
por: Rodríguez-González, Claudio, et al.
Publicado: (2020)

Optimization of expression and purification of mitochondrial HSP 40 (Tid1-L) chaperone: Role of mortalin and tid1 in the reactivation and amyloid inhibition of proteins
por: Khan, Mohammad Rashid, et al.
Publicado: (2020)

Ganoderma microsporum immunomodulatory protein, GMI, promotes C2C12 myoblast differentiation in vitro via upregulation of Tid1 and STAT3 acetylation
por: Teo, Wan-Huai, et al.
Publicado: (2020)

Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance
por: Nitika, et al.
Publicado: (2020)

Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells
por: Meshalkina, Darya A., et al.
Publicado: (2016)

Identification of a druggable protein–protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1
por: Tong, Xin, et al.
Publicado: (2020)

Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy
por: Huang, Yaping, et al.
Publicado: (2023)

Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis
por: Kotlarz, Agnieszka, et al.
Publicado: (2013)

Characterization of intrahepatic cholangiocarcinoma after curative resection: outcome, prognostic factor, and recurrence
por: Chan, Kun-Ming, et al.
Publicado: (2018)

DNAJA4 Promotes the Replication of the Chinese Giant Salamander Iridovirus
por: Liu, Zijing, et al.
Publicado: (2022)

Validation tests of the CMS TIB/TID structures
por: D'Alfonso, Mariarosaria, et al.
Publicado: (2009)

Outcomes of resection for colorectal cancer hepatic metastases stratified by evolving eras of treatment
por: Chan, Kun-Ming, et al.
Publicado: (2011)

Positive expression of Midkine predicts early recurrence and poor prognosis of initially resectable combined hepatocellular cholangiocarcinoma
por: Ma, Ming-Chun, et al.
Publicado: (2018)

Hsp70 and DNAJA2 limit CFTR levels through degradation
por: Kim Chiaw, Patrick, et al.
Publicado: (2019)

Plans for the evaluation of the TID tolerance in 65nm and below
por: Faccio, Federico
Publicado: (2018)

130nm TSMC / GF TID+SEU experience
por: Gonella, Laura, et al.
Publicado: (2020)

Combined Effect of TID Radiation and Electrical Stress on NMOSFETs
por: Cao, Yanrong, et al.
Publicado: (2022)

Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs
por: Feng, Chih-Chung, et al.
Publicado: (2018)

Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies
por: Roth, Heidi E., et al.
Publicado: (2022)

Resected Tumor Outcome and Recurrence (RESTORE) Index for Hepatocellular Carcinoma Recurrence after Resection
por: Hoffman, Daniel, et al.
Publicado: (2023)

Risk of recurrence in chronic hepatitis B patients developing hepatocellular carcinoma with antiviral secondary prevention failure
por: Lee, I-Cheng, et al.
Publicado: (2017)

HV Distributor Radiation Qualification Part Two: TID Tests
por: Chadelas, R, et al.
Publicado: (2002)

The Grounding and Shielding\\ of the\\ Tracker Inner Barrel and Disks (TIB/TID)
por: Bernardini, Jacopo, et al.
Publicado: (2009)

Development of Aptamer-Based TID Assays Using Thermophoresis and Microarrays
por: Kurth, Tracy, et al.
Publicado: (2019)

DnaJA4 is involved in responses to hyperthermia by regulating the expression of F-actin in HaCaT cells
por: Liu, Rui-Jiao, et al.
Publicado: (2021)

Tid1-S regulates the mitochondrial localization of EGFR in non-small cell lung carcinoma
por: Wang, T-H, et al.
Publicado: (2017)

DNAJA1 Stabilizes EF1A1 to Promote Cell Proliferation and Metastasis of Liver Cancer Mediated by miR-205-5p
por: Yi, Lizhi, et al.
Publicado: (2022)

Impact of metformin use on the recurrence of hepatocellular carcinoma after initial liver resection in diabetic patients
por: Cho, Wei-Ru, et al.
Publicado: (2021)

TID Tolerance of commercial 130nm CMOS Technologies for HEP experiments
por: Gonella, Laura
Publicado: (2017)

Hepatectomy or/with Metastatectomy for Recurrent Intrahepatic Cholangiocarcinoma: Of Promise for Selected Patients
por: Tsai, Chun-Yi, et al.
Publicado: (2022)

Endoscopic Resection of Residual or Recurrent Lesions after Circumferential Radiofrequency Ablation for Flat Superficial Esophageal Squamous Cell Neoplasias
por: Tsou, Yung-Kuan, et al.
Publicado: (2023)

Roles of conventional and complementary therapies in recurrent hepatocellular carcinoma
por: Lai, Hsiang-Chun, et al.
Publicado: (2023)

Risk Factors of Peritoneal Recurrence and Outcome of Resected Peritoneal Recurrence After Liver Resection in Hepatocellular Carcinoma: Review of 1222 Cases of Hepatectomy in a Tertiary Institution
por: Kow, Alfred Wei Chieh, et al.
Publicado: (2012)

Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System
por: Whitmore, Aurellia, et al.
Publicado: (2020)

The Impact of Direct-Acting Antiviral Therapy on the Risk of Recurrence after Curative Resection in Patients with Hepatitis-C-Virus-Related Early Stage Hepatocellular Carcinoma
por: Chen, Yu-Syuan, et al.
Publicado: (2022)

The role of re-resection in recurrent hepatocellular carcinoma
por: Bednarsch, Jan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5g9st82tjgv4thqefqnkt88b3n