Chaperone-Assisted Mitotic Actin Remodeling by BAG3 and HSPB8 Involves the Deacetylase HDAC6 and Its Substrate Cortactin

The fidelity of actin dynamics relies on protein quality control, but the underlying molecular mechanisms are poorly defined. During mitosis, the cochaperone BCL2-associated athanogene 3 (BAG3) modulates cell rounding, cortex stability, spindle orientation, and chromosome segregation. Mitotic BAG3 s...

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Detalles Bibliográficos
Autores principales: Luthold, Carole, Varlet, Alice-Anaïs, Lambert, Herman, Bordeleau, François, Lavoie, Josée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795263/
https://www.ncbi.nlm.nih.gov/pubmed/33375626
http://dx.doi.org/10.3390/ijms22010142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795263/
https://www.ncbi.nlm.nih.gov/pubmed/33375626
http://dx.doi.org/10.3390/ijms22010142

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