Exploring Yeast as a Study Model of Pantothenate Kinase-Associated Neurodegeneration and for the Identification of Therapeutic Compounds

Mutations in the pantothenate kinase 2 gene (PANK2) are the cause of pantothenate kinase-associated neurodegeneration (PKAN), the most common form of neurodegeneration with brain iron accumulation. Although different disease models have been created to investigate the pathogenic mechanism of PKAN, t...

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Detalles Bibliográficos
Autores principales: Ceccatelli Berti, Camilla, Gilea, Alexandru Ionut, De Gregorio, Marco Armando, Goffrini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795310/
https://www.ncbi.nlm.nih.gov/pubmed/33396642
http://dx.doi.org/10.3390/ijms22010293

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