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Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities

Evolutionary dynamics can be used to control cancers when a cure is not clinically considered to be achievable. Understanding Darwinian intratumoral interactions of microenvironmental selection forces can be used to steer tumor progression towards a less invasive trajectory. Here, we approach intrat...

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Detalles Bibliográficos
Autores principales: Ordway, Bryce, Tomaszewski, Michal, Byrne, Samantha, Abrahams, Dominique, Swietach, Pawel, Gillies, Robert J., Damaghi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795337/
https://www.ncbi.nlm.nih.gov/pubmed/33379345
http://dx.doi.org/10.3390/cancers13010064