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Functional Comparison between VP64-dCas9-VP64 and dCas9-VP192 CRISPR Activators in Human Embryonic Kidney Cells

Reversal in the transcriptional status of desired genes has been exploited for multiple research, therapeutic, and biotechnological purposes. CRISPR/dCas9-based activators can activate transcriptionally silenced genes after being guided by gene-specific gRNA(s). Here, we performed a functional compa...

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Detalles Bibliográficos
Autores principales:	Javaid, Nasir, Pham, Thuong L. H., Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795359/ https://www.ncbi.nlm.nih.gov/pubmed/33401508 http://dx.doi.org/10.3390/ijms22010397

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