Cargando…

FUT8 Alpha-(1,6)-Fucosyltransferase in Cancer

Aberrant glycosylation is a universal feature of cancer cells that can impact all steps in tumour progression from malignant transformation to metastasis and immune evasion. One key change in tumour glycosylation is altered core fucosylation. Core fucosylation is driven by fucosyltransferase 8 (FUT8...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bastian, Kayla, Scott, Emma, Elliott, David J., Munkley, Jennifer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795606/ https://www.ncbi.nlm.nih.gov/pubmed/33466384 http://dx.doi.org/10.3390/ijms22010455

Ejemplares similares

The α1,6-Fucosyltransferase Gene (fut8) from the Sf9 Lepidopteran Insect Cell Line: Insights into fut8 Evolution
por: Juliant, Sylvie, et al.
Publicado: (2014)

AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases
por: Soto, Maria J., et al.
Publicado: (2021)

The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity
por: Tomida, Seita, et al.
Publicado: (2022)

Correction: The α1,6-Fucosyltransferase Gene (fut8) from the Sf9 Lepidopteran Insect Cell Line: Insights into fut8 Evolution
Publicado: (2015)

Alpha-(1,6)-fucosyltransferase (FUT8) affects the survival strategy of osteosarcoma by remodeling TNF/NF-κB2 signaling
por: Lin, Shanyi, et al.
Publicado: (2021)

Beyond antibody fucosylation: α-(1,6)-fucosyltransferase (Fut8) as a potential new therapeutic target for cancer immunotherapy
por: Mao, Changchuin, et al.
Publicado: (2023)

Effects of MicroRNAs on Fucosyltransferase 8 (FUT8) Expression in Hepatocarcinoma Cells
por: Bernardi, Cinzia, et al.
Publicado: (2013)

Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response
por: Kyunai, Yuki M., et al.
Publicado: (2023)

Characterisation of FUT4 and FUT6 α-(1→2)-Fucosyltransferases Reveals that Absence of Root Arabinogalactan Fucosylation Increases Arabidopsis Root Growth Salt Sensitivity
por: Tryfona, Theodora, et al.
Publicado: (2014)

Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0
por: Teylaert, Béatrice, et al.
Publicado: (2011)

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish
por: Hayashiji, Nozomi, et al.
Publicado: (2022)

Expression of Fucosyltransferase 4 (FUT4) mRNA Is Increased in Endometrium from Women with Endometriosis
por: Żeberkiewicz, Marta, et al.
Publicado: (2022)

Double knockdown of α1,6-fucosyltransferase (FUT8) and GDP-mannose 4,6-dehydratase (GMD) in antibody-producing cells: a new strategy for generating fully non-fucosylated therapeutic antibodies with enhanced ADCC
por: Imai-Nishiya, Harue, et al.
Publicado: (2007)

Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase
por: García-García, Ana, et al.
Publicado: (2020)

Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells
por: Höti, Naseruddin, et al.
Publicado: (2018)

Expression of the gene encoding secretor type galactoside 2 α fucosyltransferase (FUT2) and ABH antigens in patients with oral lesions
por: Campi, Carlos, et al.
Publicado: (2012)

ST6GAL1: A key player in cancer
por: Garnham, Rebecca, et al.
Publicado: (2019)

cFUT8 promotes liver cancer progression by miR-548c/FUT8 axis
por: Li, Chong, et al.
Publicado: (2021)

Widespread Gene Conversion of Alpha-2-Fucosyltransferase Genes in Mammals
por: Abrantes, Joana, et al.
Publicado: (2009)

Glycoproteomic Characterization of FUT8 Knock-Out CHO Cells Reveals Roles of FUT8 in the Glycosylation
por: Yang, Ganglong, et al.
Publicado: (2021)

Different Effects of Androgen on the Expression of Fut1, Fut2, Fut4 and Fut9 in Male Mouse Reproductive Tract
por: Wang, Chun-Mei, et al.
Publicado: (2013)

Transcriptional activation of fucosyltransferase (FUT) genes using the CRISPR-dCas9-VPR technology reveals potent N-glycome alterations in colorectal cancer cells
por: Blanas, Athanasios, et al.
Publicado: (2018)

Expanded Proteomic Survey of the Human Parasite Leishmania major Focusing on Changes in Null Mutants of the Golgi GDP-Mannose/Fucose/Arabinopyranose Transporter LPG2 and of the Mitochondrial Fucosyltransferase FUT1
por: Polanco, Gloria, et al.
Publicado: (2022)

Glycans as Biomarkers in Prostate Cancer
por: Scott, Emma, et al.
Publicado: (2019)

Human fucosyltransferase 6 enables prostate cancer metastasis to bone
por: Li, J, et al.
Publicado: (2013)

Hallmarks of glycosylation in cancer
por: Munkley, Jennifer, et al.
Publicado: (2016)

L-Fucose treatment of FUT8-CDG
por: Park, Julien H., et al.
Publicado: (2020)

FUT8 and Protein Core Fucosylation in Tumours: From Diagnosis to Treatment
por: Liao, Chengcheng, et al.
Publicado: (2021)

Comparing the Immunoexpression of FUT3 and FUT6 between Prostatic Adenocarcinoma and Benign Prostatic Hyperplasia
por: de Albuquerque Vasconcelos, Juliana Lúcia, et al.
Publicado: (2013)

Biochemical and physiological characterization of fut4 and fut6 mutants defective in arabinogalactan-protein fucosylation in Arabidopsis
por: Liang, Yan, et al.
Publicado: (2013)

Inhibition of α(1,6)fucosyltransferase: Effects on Cell Proliferation, Migration, and Adhesion in an SW480/SW620 Syngeneic Colorectal Cancer Model
por: López-Cortés, Rubén, et al.
Publicado: (2022)

Fucosyltransferase 8 is Overexpressed and Influences Clinical Outcomes in Lung Adenocarcinoma Patients
por: Liang, Yiqian, et al.
Publicado: (2022)

Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancer
por: Advani, Rahul, et al.
Publicado: (2023)

Targeting Aberrant Sialylation to Treat Cancer
por: Munkley, Jennifer, et al.
Publicado: (2019)

Futs and the Higgs-boson
por: Heinemeyer, Sven, et al.
Publicado: (2012)

Characterization of bovine FUT7 furthers understanding of FUT7 evolution in mammals
por: Laporte, Benoît, et al.
Publicado: (2012)

N (6)‐methyladenosine‐modified circFUT8 competitively interacts with YTHDF2 and miR‐186‐5p to stabilize FUT8 mRNA to promote malignant progression in lung adenocarcinoma
por: Dong, Gaochao, et al.
Publicado: (2023)

Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2γ
por: Ma, Minxing, et al.
Publicado: (2021)

RNA splicing and splicing regulator changes in prostate cancer pathology
por: Munkley, Jennifer, et al.
Publicado: (2017)

Loss of α1,6-fucosyltransferase suppressed liver regeneration: implication of core fucose in the regulation of growth factor receptor-mediated cellular signaling
por: Wang, Yuqin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_islv77rq66otpift81fl7mcib6