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Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate

Male hypogonadism is often treated by testosterone (T) replacement therapy such as oral administration of the ester prodrug, testosterone undecanoate (TU). However, the systemic exposure to T following oral TU is very low due to esterase-mediated metabolism, particularly in the small intestine. The...

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Detalles Bibliográficos
Autores principales: Zgair, Atheer, Dawood, Yousaf, Ibrahem, Suhaib M., Lee, Jong Bong, Feng, Wanshan, Fischer, Peter M., Gershkovich, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795771/
https://www.ncbi.nlm.nih.gov/pubmed/33466340
http://dx.doi.org/10.3390/molecules26010233