Cargando…
AMP-Activated Protein Kinase: Do We Need Activators or Inhibitors to Treat or Prevent Cancer?
AMP-activated protein kinase (AMPK) is a key regulator of cellular energy balance. In response to metabolic stress, it acts to redress energy imbalance through promotion of ATP-generating catabolic processes and inhibition of ATP-consuming processes, including cell growth and proliferation. While fi...
Autores principales: | Russell, Fiona M., Hardie, David Grahame |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795930/ https://www.ncbi.nlm.nih.gov/pubmed/33375416 http://dx.doi.org/10.3390/ijms22010186 |
Ejemplares similares
-
Regulation of AMP-activated protein kinase by natural and synthetic activators
por: Grahame Hardie, David
Publicado: (2016) -
AMP-activated protein kinase – not just an energy sensor
por: Hardie, David Grahame, et al.
Publicado: (2017) -
Keeping the home fires burning(†): AMP-activated protein kinase
por: Hardie, D. Grahame
Publicado: (2018) -
AMP-activated protein kinase: a target for drugs both ancient and modern
por: Hardie, D. Grahame, et al.
Publicado: (2012) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
por: Gowans, Graeme J., et al.
Publicado: (2013)