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The Activity and Stability of p56Lck and TCR Signaling Do Not Depend on the Co-Chaperone Cdc37
Lymphocyte-specific protein tyrosine kinase (Lck) is a pivotal tyrosine kinase involved in T cell receptor (TCR) signaling. Because of its importance, the activity of Lck is regulated at different levels including phosphorylation of tyrosine residues, protein–protein interactions, and localization....
Autores principales: | Kowallik, Sarah, Kritikos, Andreas, Kästle, Matthias, Thurm, Christoph, Schraven, Burkhart, Simeoni, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7795971/ https://www.ncbi.nlm.nih.gov/pubmed/33374422 http://dx.doi.org/10.3390/ijms22010126 |
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