HIV-1 Tat Protein Enters Dysfunctional Endothelial Cells via Integrins and Renders Them Permissive to Virus Replication

Previous work has shown that the Tat protein of Human Immunodeficiency Virus (HIV)-1 is released by acutely infected cells in a biologically active form and enters dendritic cells upon the binding of its arginine-glycine-aspartic acid (RGD) domain to the α5β1, αvβ3, and αvβ5 integrins. The up-regula...

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Detalles Bibliográficos
Autores principales: Cafaro, Aurelio, Barillari, Giovanni, Moretti, Sonia, Palladino, Clelia, Tripiciano, Antonella, Falchi, Mario, Picconi, Orietta, Pavone Cossut, Maria Rosaria, Campagna, Massimo, Arancio, Angela, Sgadari, Cecilia, Andreini, Claudia, Banci, Lucia, Monini, Paolo, Ensoli, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796023/
https://www.ncbi.nlm.nih.gov/pubmed/33396807
http://dx.doi.org/10.3390/ijms22010317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796023/
https://www.ncbi.nlm.nih.gov/pubmed/33396807
http://dx.doi.org/10.3390/ijms22010317

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