Cargando…

Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart

Stearoyl-CoA desaturase 1 (SCD1), an enzyme that is involved in the biosynthesis of monounsaturated fatty acids, induces the reprogramming of cardiomyocyte metabolism. Thyroid hormones (THs) activate both lipolysis and lipogenesis. Many genes that are involved in lipid metabolism, including Scd1, ar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olichwier, Adam, Balatskyi, Volodymyr V., Wolosiewicz, Marcin, Ntambi, James M., Dobrzyn, Pawel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796080/ https://www.ncbi.nlm.nih.gov/pubmed/33374300 http://dx.doi.org/10.3390/ijms22010109

Ejemplares similares

Role of Stearoyl-CoA Desaturase 1 in Cardiovascular Physiology
por: Balatskyi, Volodymyr V., et al.
Publicado: (2023)

Stearoyl-CoA Desaturase Regulates Angiogenesis and Energy Metabolism in Ischemic Cardiomyocytes
por: Gan, Ana-Maria, et al.
Publicado: (2022)

Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
por: Tracz-Gaszewska, Zuzanna, et al.
Publicado: (2019)

Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease
por: O’Neill, Lucas M., et al.
Publicado: (2020)

Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase
por: Shi, Xun, et al.
Publicado: (2013)

Stearoyl-CoA Desaturase 1 Activity Determines the Maintenance of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells
por: Dobosz, Aneta M., et al.
Publicado: (2020)

Global deficiency of stearoyl-CoA desaturase-2 protects against diet-induced adiposity
por: O’Neill, Lucas M., et al.
Publicado: (2020)

The Evolutionary Pattern and the Regulation of Stearoyl-CoA Desaturase Genes
por: Wu, Xiaoyun, et al.
Publicado: (2013)

Stearoyl-CoA Desaturase Is Essential for Porcine Adipocyte Differentiation
por: Liu, Lulu, et al.
Publicado: (2020)

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
por: Bogie, Jeroen F.J., et al.
Publicado: (2020)

Increased hydrophilic plasma bile acids are correlated with protection from adiposity in skin-specific stearoyl-CoA desaturase-1 deficient mice
por: Dumas, Sabrina N., et al.
Publicado: (2018)

Stearoyl-CoA Desaturase-1: Is It the Link between Sulfur Amino Acids and Lipid Metabolism?
por: Poloni, Soraia, et al.
Publicado: (2015)

The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates
por: Castro, L Filipe C, et al.
Publicado: (2011)

Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
por: Astarita, Giuseppe, et al.
Publicado: (2011)

X-ray Structure of a Mammalian Stearoyl-CoA Desaturase
por: Bai, Yonghong, et al.
Publicado: (2015)

Discovery of Tumor-Specific Irreversible Inhibitors of Stearoyl CoA Desaturase
por: Theodoropoulos, Panayotis C., et al.
Publicado: (2016)

Compensatory increases in tear volume and mucin levels associated with meibomian gland dysfunction caused by stearoyl-CoA desaturase-1 deficiency
por: Inaba, Takaaki, et al.
Publicado: (2018)

Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity
por: Grajchen, Elien, et al.
Publicado: (2023)

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression
por: Li, Weihua, et al.
Publicado: (2018)

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer
por: Oatman, Nicole, et al.
Publicado: (2021)

Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages
por: Lin, Joseph B., et al.
Publicado: (2023)

Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma
por: Ducheix, Simon, et al.
Publicado: (2022)

Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions
por: Breuer, Sebastian, et al.
Publicado: (2004)

Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells
por: Wang, Lingling, et al.
Publicado: (2022)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1)
por: Piccinin, Elena, et al.
Publicado: (2019)

Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1
por: Cook, Katherine, et al.
Publicado: (2014)

Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas
por: Dobosz, Aneta M., et al.
Publicado: (2022)

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells
por: Noto, A, et al.
Publicado: (2013)

Fatty Liver Is Associated with Transcriptional Downregulation of Stearoyl-CoA Desaturase and Impaired Protein Dimerization
por: Fernández Gianotti, Tomas, et al.
Publicado: (2013)

Increased expression of the gene encoding stearoyl-CoA desaturase 1 in human bladder cancer
por: Presler, M., et al.
Publicado: (2018)

A hint from zebrafish models of hepatic tumorigenesis: Targeting stearoyl-CoA desaturase
por: Lv, Kunpeng, et al.
Publicado: (2019)

Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
por: Zhou, Xian, et al.
Publicado: (2021)

A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity
por: Nuber, Silke, et al.
Publicado: (2022)

Stearoyl-CoA Desaturase 1 as a Therapeutic Biomarker: Focusing on Cancer Stem Cells
por: Min, Jin-Young, et al.
Publicado: (2023)

Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes
por: Rodriguez-Cuenca, Sergio, et al.
Publicado: (2016)

Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer
por: Zhang, Yana, et al.
Publicado: (2022)

A high activity index of stearoyl-CoA desaturase is associated with increased risk of fracture in men
por: Melhus, H., et al.
Publicado: (2007)

The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis
por: AbuAli, G, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_s53pb9vnleul9s355ma61qa2v9