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Modeling the Dynamics of Drug Spreading in China

Drug abuse remains one of the major public health issues at the global level. In this article, we propose a drug epidemic model with a complete addiction–rehabilitation–recovery process, which allows the initiation of new users under the influence of drug addicts undergoing treatment and hidden drug...

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Detalles Bibliográficos
Autores principales: Tang, Haoxiang, Li, Mingtao, Yan, Xiangyu, Lu, Zuhong, Jia, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796082/
https://www.ncbi.nlm.nih.gov/pubmed/33401693
http://dx.doi.org/10.3390/ijerph18010288
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author Tang, Haoxiang
Li, Mingtao
Yan, Xiangyu
Lu, Zuhong
Jia, Zhongwei
author_facet Tang, Haoxiang
Li, Mingtao
Yan, Xiangyu
Lu, Zuhong
Jia, Zhongwei
author_sort Tang, Haoxiang
collection PubMed
description Drug abuse remains one of the major public health issues at the global level. In this article, we propose a drug epidemic model with a complete addiction–rehabilitation–recovery process, which allows the initiation of new users under the influence of drug addicts undergoing treatment and hidden drug addicts. We first conduct qualitative analyses of the dynamical behaviors of the model, including the existence and positivity of the solutions, the basic reproduction number, global asymptotic stabilities of both the drug-free and the drug-persistent equilibria, as well as sensitivity analysis. Then we use the model to predict the drug epidemic in China during 2020–2030. Finally, we numerically simulate the potential impact of intervention strategies on different drug users. The results show that the drug epidemic will decrease significantly during 2020−2030, and the most effective intervention strategy to eliminate drug epidemics is to strengthen the investigation and rehabilitation admission of hidden drug users.
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spelling pubmed-77960822021-01-10 Modeling the Dynamics of Drug Spreading in China Tang, Haoxiang Li, Mingtao Yan, Xiangyu Lu, Zuhong Jia, Zhongwei Int J Environ Res Public Health Article Drug abuse remains one of the major public health issues at the global level. In this article, we propose a drug epidemic model with a complete addiction–rehabilitation–recovery process, which allows the initiation of new users under the influence of drug addicts undergoing treatment and hidden drug addicts. We first conduct qualitative analyses of the dynamical behaviors of the model, including the existence and positivity of the solutions, the basic reproduction number, global asymptotic stabilities of both the drug-free and the drug-persistent equilibria, as well as sensitivity analysis. Then we use the model to predict the drug epidemic in China during 2020–2030. Finally, we numerically simulate the potential impact of intervention strategies on different drug users. The results show that the drug epidemic will decrease significantly during 2020−2030, and the most effective intervention strategy to eliminate drug epidemics is to strengthen the investigation and rehabilitation admission of hidden drug users. MDPI 2021-01-02 2021-01 /pmc/articles/PMC7796082/ /pubmed/33401693 http://dx.doi.org/10.3390/ijerph18010288 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tang, Haoxiang
Li, Mingtao
Yan, Xiangyu
Lu, Zuhong
Jia, Zhongwei
Modeling the Dynamics of Drug Spreading in China
title Modeling the Dynamics of Drug Spreading in China
title_full Modeling the Dynamics of Drug Spreading in China
title_fullStr Modeling the Dynamics of Drug Spreading in China
title_full_unstemmed Modeling the Dynamics of Drug Spreading in China
title_short Modeling the Dynamics of Drug Spreading in China
title_sort modeling the dynamics of drug spreading in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796082/
https://www.ncbi.nlm.nih.gov/pubmed/33401693
http://dx.doi.org/10.3390/ijerph18010288
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AT jiazhongwei modelingthedynamicsofdrugspreadinginchina