Cargando…

Multi-Interactions in Ionic Liquids for Natural Product Extraction

Natural products with a variety of pharmacological effects are important sources for commercial drugs, and it is very crucial to develop effective techniques to selectively extract and isolate bioactive natural components from the plants against the background of sustainable development. Ionic liqui...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ying, Cao, Yingying, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796109/
https://www.ncbi.nlm.nih.gov/pubmed/33379318
http://dx.doi.org/10.3390/molecules26010098
_version_ 1783634603653726208
author Zhang, Ying
Cao, Yingying
Wang, Hui
author_facet Zhang, Ying
Cao, Yingying
Wang, Hui
author_sort Zhang, Ying
collection PubMed
description Natural products with a variety of pharmacological effects are important sources for commercial drugs, and it is very crucial to develop effective techniques to selectively extract and isolate bioactive natural components from the plants against the background of sustainable development. Ionic liquids (ILs) are a kind of designable material with unique physicochemical properties, including good thermal stability, negligible vapor pressure, good solvation ability, etc. ILs have already been used in pharmaceuticals for extraction, purification, drug delivery, etc. It has been reported that multi-interactions, like hydrogen bonding, hydrophobic interactions, play important roles in the extraction of bioactive components from the plants. In this review, recent progress in the understanding of scientific essence of hydrogen bonding, the special interaction, in ILs was summarized. The extraction of various natural products, one important area in pharmaceutical, by conventional and functional ILs as well as the specific roles of multi-interactions in this process were also reviewed. Moreover, problems existing in bioactive compound extraction by ILs and the future developing trends of this area are given, which might be helpful for scientists, especially beginners, in this field.
format Online
Article
Text
id pubmed-7796109
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77961092021-01-10 Multi-Interactions in Ionic Liquids for Natural Product Extraction Zhang, Ying Cao, Yingying Wang, Hui Molecules Review Natural products with a variety of pharmacological effects are important sources for commercial drugs, and it is very crucial to develop effective techniques to selectively extract and isolate bioactive natural components from the plants against the background of sustainable development. Ionic liquids (ILs) are a kind of designable material with unique physicochemical properties, including good thermal stability, negligible vapor pressure, good solvation ability, etc. ILs have already been used in pharmaceuticals for extraction, purification, drug delivery, etc. It has been reported that multi-interactions, like hydrogen bonding, hydrophobic interactions, play important roles in the extraction of bioactive components from the plants. In this review, recent progress in the understanding of scientific essence of hydrogen bonding, the special interaction, in ILs was summarized. The extraction of various natural products, one important area in pharmaceutical, by conventional and functional ILs as well as the specific roles of multi-interactions in this process were also reviewed. Moreover, problems existing in bioactive compound extraction by ILs and the future developing trends of this area are given, which might be helpful for scientists, especially beginners, in this field. MDPI 2020-12-28 /pmc/articles/PMC7796109/ /pubmed/33379318 http://dx.doi.org/10.3390/molecules26010098 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Ying
Cao, Yingying
Wang, Hui
Multi-Interactions in Ionic Liquids for Natural Product Extraction
title Multi-Interactions in Ionic Liquids for Natural Product Extraction
title_full Multi-Interactions in Ionic Liquids for Natural Product Extraction
title_fullStr Multi-Interactions in Ionic Liquids for Natural Product Extraction
title_full_unstemmed Multi-Interactions in Ionic Liquids for Natural Product Extraction
title_short Multi-Interactions in Ionic Liquids for Natural Product Extraction
title_sort multi-interactions in ionic liquids for natural product extraction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796109/
https://www.ncbi.nlm.nih.gov/pubmed/33379318
http://dx.doi.org/10.3390/molecules26010098
work_keys_str_mv AT zhangying multiinteractionsinionicliquidsfornaturalproductextraction
AT caoyingying multiinteractionsinionicliquidsfornaturalproductextraction
AT wanghui multiinteractionsinionicliquidsfornaturalproductextraction