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Effects of Eltrombopag on In Vitro Macrophage Polarization in Pediatric Immune Thrombocytopenia
Immune Thrombocytopenia (ITP) is an autoimmune disease characterized by autoantibodies-mediated platelet destruction, a prevalence of M1 pro-inflammatory macrophage phenotype and an elevated T helper 1 and T helper 2 lymphocytes (Th1/Th2) ratio, resulting in impairment of inflammatory profile and im...
Autores principales: | Di Paola, Alessandra, Palumbo, Giuseppe, Merli, Pietro, Argenziano, Maura, Tortora, Chiara, Strocchio, Luisa, Roberti, Domenico, Santoro, Claudia, Perrotta, Silverio, Rossi, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796119/ https://www.ncbi.nlm.nih.gov/pubmed/33374151 http://dx.doi.org/10.3390/ijms22010097 |
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