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LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma—Potential Biomarkers for Targeted Therapy Concepts

Tumor growth and survival requires a particularly effective immunosuppressant tumor microenvironment (TME) to escape destruction by the immune system. While immunosuppressive checkpoint markers like programmed cell death 1 ligand (PD-L1) are already being targeted in clinical practice, lymphocyte-ac...

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Detalles Bibliográficos
Autores principales: Wuerdemann, Nora, Pütz, Katharina, Eckel, Hans, Jain, Rishabh, Wittekindt, Claus, Huebbers, Christian U., Sharma, Shachi J., Langer, Christine, Gattenlöhner, Stefan, Büttner, Reinhard, Speel, Ernst-Jan, Suchan, Malte, Wagner, Steffen, Quaas, Alexander, Klussmann, Jens P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796181/
https://www.ncbi.nlm.nih.gov/pubmed/33396515
http://dx.doi.org/10.3390/ijms22010379