Cargando…

Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing

The advent of 3D digital printers has led to the evolution of realistic anatomical organ shaped structures that are being currently used as experimental models for rehearsing and preparing complex surgical procedures by clinicians. However, the actual material properties are still far from being ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Heo, Hyeonu, Jin, Yuqi, Yang, David, Wier, Christopher, Minard, Aaron, Dahotre, Narendra B., Neogi, Arup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796254/
https://www.ncbi.nlm.nih.gov/pubmed/33396859
http://dx.doi.org/10.3390/polym13010123
_version_ 1783634638703427584
author Heo, Hyeonu
Jin, Yuqi
Yang, David
Wier, Christopher
Minard, Aaron
Dahotre, Narendra B.
Neogi, Arup
author_facet Heo, Hyeonu
Jin, Yuqi
Yang, David
Wier, Christopher
Minard, Aaron
Dahotre, Narendra B.
Neogi, Arup
author_sort Heo, Hyeonu
collection PubMed
description The advent of 3D digital printers has led to the evolution of realistic anatomical organ shaped structures that are being currently used as experimental models for rehearsing and preparing complex surgical procedures by clinicians. However, the actual material properties are still far from being ideal, which necessitates the need to develop new materials and processing techniques for the next generation of 3D printers optimized for clinical applications. Recently, the voxelated soft matter technique has been introduced to provide a much broader range of materials and a profile much more like the actual organ that can be designed and fabricated voxel by voxel with high precision. For the practical applications of 3D voxelated materials, it is crucial to develop the novel high precision material manufacturing and characterization technique to control the mechanical properties that can be difficult using the conventional methods due to the complexity and the size of the combination of materials. Here we propose the non-destructive ultrasound effective density and bulk modulus imaging to evaluate 3D voxelated materials printed by J750 Digital Anatomy 3D Printer of Stratasys. Our method provides the design map of voxelated materials and substantially broadens the applications of 3D digital printing in the clinical research area.
format Online
Article
Text
id pubmed-7796254
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77962542021-01-10 Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing Heo, Hyeonu Jin, Yuqi Yang, David Wier, Christopher Minard, Aaron Dahotre, Narendra B. Neogi, Arup Polymers (Basel) Article The advent of 3D digital printers has led to the evolution of realistic anatomical organ shaped structures that are being currently used as experimental models for rehearsing and preparing complex surgical procedures by clinicians. However, the actual material properties are still far from being ideal, which necessitates the need to develop new materials and processing techniques for the next generation of 3D printers optimized for clinical applications. Recently, the voxelated soft matter technique has been introduced to provide a much broader range of materials and a profile much more like the actual organ that can be designed and fabricated voxel by voxel with high precision. For the practical applications of 3D voxelated materials, it is crucial to develop the novel high precision material manufacturing and characterization technique to control the mechanical properties that can be difficult using the conventional methods due to the complexity and the size of the combination of materials. Here we propose the non-destructive ultrasound effective density and bulk modulus imaging to evaluate 3D voxelated materials printed by J750 Digital Anatomy 3D Printer of Stratasys. Our method provides the design map of voxelated materials and substantially broadens the applications of 3D digital printing in the clinical research area. MDPI 2020-12-30 /pmc/articles/PMC7796254/ /pubmed/33396859 http://dx.doi.org/10.3390/polym13010123 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Heo, Hyeonu
Jin, Yuqi
Yang, David
Wier, Christopher
Minard, Aaron
Dahotre, Narendra B.
Neogi, Arup
Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title_full Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title_fullStr Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title_full_unstemmed Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title_short Manufacturing and Characterization of Hybrid Bulk Voxelated Biomaterials Printed by Digital Anatomy 3D Printing
title_sort manufacturing and characterization of hybrid bulk voxelated biomaterials printed by digital anatomy 3d printing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796254/
https://www.ncbi.nlm.nih.gov/pubmed/33396859
http://dx.doi.org/10.3390/polym13010123
work_keys_str_mv AT heohyeonu manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT jinyuqi manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT yangdavid manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT wierchristopher manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT minardaaron manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT dahotrenarendrab manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting
AT neogiarup manufacturingandcharacterizationofhybridbulkvoxelatedbiomaterialsprintedbydigitalanatomy3dprinting