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Pick’s Tau Fibril Shows Multiple Distinct PET Probe Binding Sites: Insights from Computational Modelling

In recent years, it has been realized that the tau protein is a key player in multiple neurodegenerative diseases. Positron emission tomography (PET) radiotracers that bind to tau filaments in Alzheimer’s disease (AD) are in common use, but PET tracers binding to tau filaments of rarer, age-related...

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Detalles Bibliográficos
Autores principales: Mishra, Sushil K., Yamaguchi, Yoshiki, Higuchi, Makoto, Sahara, Naruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796283/
https://www.ncbi.nlm.nih.gov/pubmed/33396273
http://dx.doi.org/10.3390/ijms22010349

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