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Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression

Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment towards an immune suppressive state. Transforming growth factor-β (TGF-β) is a secreted multifunctional cytokine that strongly regulates the activity of immune cells while, in parallel, can promote malig...

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Detalles Bibliográficos
Autores principales:	van den Bulk, Jitske, de Miranda, Noel F.C.C., ten Dijke, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7796313/ https://www.ncbi.nlm.nih.gov/pubmed/33399850 http://dx.doi.org/10.1042/CS20201236

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